Guidelines for drug treatment of Alzheimer's disease

Yuhui LIU, Xianle BU, Xin MA, Gang WANG, Hongzheng WANG, Guihong WANG, Feiqi ZHU, Liyan QIAO, Zhaorui LIU, Yong JI, Xiaofeng LI, Yanfeng LI, Xia LI, Weizhong XIAO, Shifu XIAO, Qingjian WU, Wei ZHANG, Jintai YU, Yuying ZHOU, Qinghua HOU, Junliang YUAN, Jianjun JIA, Yun GU, Ling GUO, Qihao GUO, Dantao PENG, Zhong PEI, Weigang PAN, Yanjiang WANG, Jun WANG, China Association for Alzheimer's Disease

Chinese Journal of Alzheimer's Disease and Related Disorders ›› 2025, Vol. 8 ›› Issue (1) : 8-16.

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Chinese Journal of Alzheimer's Disease and Related Disorders

Abbreviation (ISO4): Chinese Journal of Alzheimer's Disease and Related Disorders      Editor in chief: Jun WANG

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Chinese Journal of Alzheimer's Disease and Related Disorders ›› 2025, Vol. 8 ›› Issue (1) : 8-16. DOI: 10.3969/j.issn.2096-5516.2025.01.002

Guidelines for drug treatment of Alzheimer's disease

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Abstract

Based on current literature and expert panel discussions, the recommendations for drug treatment of Alzheimer's disease (AD) have been updated in accordance with previous guidelines on the diagnosis and treatment of dementia and cognitive impairment. The update emphasizes the advancements in anti-Aβ immunotherapy, with the aim of providing a reference for early and comprehensive intervention for AD. The content covers the following key aspects: the principles of AD treatment; symptomatic medications, including cholinesterase inhibitors and NMDA receptor antagonists; management of behavioral and psychological symptoms; disease-modifying therapies such as Aducanumab, Lecanemab, and Donanemab; the use of Sodium Oligomannate; and the use of traditional Chinese medicine.

Key words

Alzheimer's disease / Drug treatment / Amyloid beta protein / Immunotherapy / Guidelines

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Yuhui LIU , Xianle BU , Xin MA , et al . Guidelines for drug treatment of Alzheimer's disease[J]. Chinese Journal of Alzheimer's Disease and Related Disorders. 2025, 8(1): 8-16 https://doi.org/10.3969/j.issn.2096-5516.2025.01.002

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