Progress in the research of rTMS in the rehabilitation treatment of post-stroke cognitive impairment

Rui ZHANG, Zhongyue LYU, Zhiwei XU

Chinese Journal of Alzheimer's Disease and Related Disorders ›› 2025, Vol. 8 ›› Issue (1) : 61-66.

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Chinese Journal of Alzheimer's Disease and Related Disorders

Abbreviation (ISO4): Chinese Journal of Alzheimer's Disease and Related Disorders      Editor in chief: Jun WANG

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Chinese Journal of Alzheimer's Disease and Related Disorders ›› 2025, Vol. 8 ›› Issue (1) : 61-66. DOI: 10.3969/j.issn.2096-5516.2025.01.009

Progress in the research of rTMS in the rehabilitation treatment of post-stroke cognitive impairment

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Abstract

Cerebral stroke, a severe cerebrovascular disease causing acute brain dysfunction, imposes a heavy burden on families and society due to its high incidence and disability rates. Patients often develop post-stroke cognitive impairment (PSCI) after stroke, which affects multiple cognitive dimensions including memory, executive function, attention, language, and visuospatial abilities. Traditional rehabilitation therapies, although somewhat effective in promoting cognitive recovery, generally suffer from slow onset, long treatment cycles, and patient compliance issues. In recent years, repetitive transcranial magnetic stimulation (rTMS), as an emerging neuromodulation technique, has shown positive effects on the cognitive function of PSCI patients by continuously applying high-intensity, transient magnetic pulses to the brain tissue, effectively modulating the excitatory state of the cerebral cortex. This review aims to summarize the mechanisms of action and clinical research progress of rTMS in the treatment of PSCI, providing a scientific basis for clinical treatment planning and inspiring future research directions.

Key words

Post-Stroke cognitive impairment / Repetitive transcranial magnetic stimulation / Neuromodulation / Rehabilitation therapy

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Rui ZHANG , Zhongyue LYU , Zhiwei XU. Progress in the research of rTMS in the rehabilitation treatment of post-stroke cognitive impairment[J]. Chinese Journal of Alzheimer's Disease and Related Disorders. 2025, 8(1): 61-66 https://doi.org/10.3969/j.issn.2096-5516.2025.01.009

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Footnotes

利益冲突:除基金项目支持外,本文无个人或企业的经济利益。

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