Abbreviation (ISO4): Chinese Journal of Alzheimer's Disease and Related Disorders
Editor in chief: Jun WANG
Chinese Journal of Alzheimer's Disease and Related Disorders >
A comparative study on the identification of amnestic mild cognitive impairment with MOCA-B and MES scales
Received date: 2020-11-04
Revised date: 2020-12-05
Online published: 2021-03-25
Expect to find the sensitivity and specificity of the Montreal Cognitive Assessment-Basic (MOCA-B) scales and Memory and Executive Screening (MES) scales of Guoqihao versionon Amnestic mild cognitive impairment (aMCI).
Sixty-eight (68) patients with memory decline were recuited in this study and evaluated by neuropsychological tests (NPT), according to aMCI standard of Petersen.
The patients were divided into aMCI group (n=48) and normal group (n=20). The sensitivity of MOCA-B and MES were 93.75% and 72.92% respectively (P=0.01), and the specificity of MOCA-B and MES were 75% and 85% respectively (P=1.00).
The sensitivity of MOCA-B scale was significantly better than MES on aMCI, and it need to be studied further.
Key words: Mild cognitive impairment; MES scale; MOCA-B scale; Sensitivity; Specificity
XU Chunyan , CHEN Chunchun , GUO Qiwen , LIN Yanwei , MENG Xueya , QIU Guozhen , ZHU Feiqi . A comparative study on the identification of amnestic mild cognitive impairment with MOCA-B and MES scales[J]. Chinese Journal of Alzheimer's Disease and Related Disorders, 2021 , 4(1) : 33 -36 . DOI: 10.3969/j.issn.2096-5516.2021.01.005
表1 一般临床资料Tab.1 General clinical data |
aMCI组 n=48 | 正常组 n=20 | |
---|---|---|
年龄 | 68.71±9.58 | 63.05±11.57 |
男性 | 17(35.4) | 5(25.0) |
受教育年限 | 10.12±4.72 | 12.45±3.46 |
高血压史 | 15(31.2) | 3(15.0) |
糖尿病史 | 5(10.4) | 1(5.0) |
脑卒中史 | 2(4.2) | 0(0) |
脑外伤史 | 3(6.2) | 0(0) |
癫痫史 | 0(0) | 1(5.0) |
全麻手术史 | 9(18.8) | 4(20.0) |
痴呆家族史 | 4(8.3) | 3(15.0) |
Note: percentages presented in brackets |
表2 两组各测验的结果对比Tab.2 The results of each test were compared between the two groups |
测验 | aMCI组(n=48) | 正常组(n=20) | P值 |
---|---|---|---|
MMSE总分 | 23.4±4.5 | 28.5±1.2 | 0.000 |
MOCA-B总分 | 17.6±4.8 | 25.2±2.7 | 0.000 |
MES总分 | 66.6±15.8 | 84.9±7.9 | 0.000 |
AVLT-H总回忆 | 16.1±8.8 | 31.1±7.7 | 0.000 |
AVLT-H长延迟回忆 | 1.7±1.5 | 6.2±2.0 | 0.000 |
CFT复杂图形模仿 | 25.8±10.9 | 34.5±1.5 | 0.000 |
CFT复杂图形延迟回忆 | 5.9±3.8 | 17.5±7.3 | 0.000 |
动物流畅性总分 | 11.1±3.9 | 14.9±3.3 | 0.000 |
Boston命名测验 | 18.0±4.5 | 23.1±2.9 | 0.000 |
Stroop 色词测验C正确数 | 43.2±8.5 | 48.0±1.7 | 0.001 |
连线测验(STT-B)耗时数(秒) | 276.7±95.9 | 159.2±42.9 | 0.000 |
表3 MOCA-B和MES量表对aMCI的诊断评价Tab.3 Diagnostic evaluation of moca-b and MES scale for aMCI |
诊断指标 | MOCA-B量表 | MES量表 | P值 |
---|---|---|---|
敏感性 | 93.75% | 72.92% | 0.01 |
特异性 | 75% | 85% | 1.00 |
Youden指数 | 0.69 | 0.58 |
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