Abbreviation (ISO4): Chinese Journal of Alzheimer's Disease and Related Disorders
Editor in chief: Jun WANG
Chinese Journal of Alzheimer's Disease and Related Disorders >
Chronic inflammatory demyelinating polyradiculoneuropathy with Parkinsonian syndrome: 2 case reports
Received date: 2020-06-10
Revised date: 2020-09-05
Online published: 2020-12-25
Objective: To explore the relationship between chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and Parkinsonian syndrome.Methods: The clinical data of 2 CIDP patients with Parkinsonian syndrome were reported and analyzed, combined with relevant literature review. Results: The medical history of the two patients was characterized by chronic onset, gradual progress and multiple relapses. The clinical manifestations were consistent with CIDP. On this basis, the two patients were complicated with tremor and bradykinesia of both upper limbs. All of them met the diagnostic criteria of Partinsonian syndrome. The tremor of case 1 was earlier than that of numbness and weakness of limbs. It was postural and resting tremor, which was limited to both upper limbs. The symptoms of case 1 responded well to immunoglobulin and glucocorticoid. In case 2, the tremor of both hands occurred later than that of numbness and weakness of both lower limbs, which was intentional tremor combined with resting tremor, with small amplitude and poor therapeutic effect. Conclusion: Parkinsonian syndrome can be regarded as a rare clinical manifestation of CIDP. The etiological treatment for CIDP combined with anti-Parkinsonian treatment may improve the symptoms of Parkinsonian syndrome.
YUAN Yongsheng , GAN Caiting , ZHANG Hui , SHEN Feifei , ZHANG Kezhong . Chronic inflammatory demyelinating polyradiculoneuropathy with Parkinsonian syndrome: 2 case reports[J]. Chinese Journal of Alzheimer's Disease and Related Disorders, 2020 , 3(4) : 284 -287 . DOI: 10.3969/j.issn.2096-5516.2020.04.005
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