The paper deals with the soil and fertilizer information system.VB6.0 was selected as development tool to develop the information system information system for soil, fertilizer and agro-chemistry service in Anhui province. The system was made by the program design of modules and ActiveX technique with consumer interface of dialog frame under windows. The whole system was divided nine parts providing the information about soil nutrient state, fertilizer experiments, crop planting, agro-chemistry service, new type fertilizer and production, fertilizer management, industry departments and fertilizer enterprises in Anhui Province. The inputs of nitrogen, phosphorous, potassium fertilizers could be determined with the system according to selected place name on map, crop kind and expected yield, possessing the decision support function for component recommendation and raw materials mixing of compound fertilizer .