Abbreviation (ISO4): Chinese Journal of Alzheimer's Disease and Related Disorders
Editor in chief: Jun WANG
Chinese Journal of Alzheimer's Disease and Related Disorders >
Neuropsychological and neuroimaging characteristics of early-onset and late-onset Alzheimer’s disease
Received date: 2019-07-10
Revised date: 2019-07-17
Online published: 2019-12-25
Alzheimer’s disease (AD) can be classified into early-onset Alzheimer’s disease (EOAD) and late-onset Alzheimer’s disease (LOAD), depending on the age of disease onset. Thereinto, EOAD shows a rapid progression after onset and thus requires earlier diagnosis. Identification of differences in clinical manifestations, including the imaging features, would be important in early detection of the two subtypes. Although EOAD patients can be confirmed with special symptoms, including visuo-spatial dysfunctions, there still remains other overlaps between EOAD and LOAD which requires an early and accurate diagnosis. This review provides an overview of two subtypes and tries to provide some references for diagnosis, especially for EOAD.
LI Zheyu , LI Kaicheng , ZENG Qingze , CHEN Yanxing , ZHANG Minming . Neuropsychological and neuroimaging characteristics of early-onset and late-onset Alzheimer’s disease[J]. Chinese Journal of Alzheimer's Disease and Related Disorders, 2019 , 2(4) : 537 -543 . DOI: 10.3969/j.issn.2096-5516.2019.04.014
[1] |
|
[2] |
|
[3] |
|
[4] |
|
[5] |
|
[6] |
|
[7] |
Jack,
|
[8] |
|
[9] |
|
[10] |
|
[11] |
|
[12] |
|
[13] |
|
[14] |
|
[15] |
|
[16] |
|
[17] |
|
[18] |
|
[19] |
|
[20] |
|
[21] |
|
[22] |
|
[23] |
|
[24] |
|
[25] |
|
[26] |
|
[27] |
|
[28] |
|
[29] |
|
[30] |
|
[31] |
|
[32] |
|
[33] |
|
[34] |
|
[35] |
|
[36] |
|
[37] |
|
[38] |
|
[39] |
|
[40] |
|
[41] |
|
[42] |
|
[43] |
|
[44] |
|
[45] |
|
[46] |
|
[47] |
|
[48] |
|
[49] |
|
[50] |
|
[51] |
|
[52] |
|
[53] |
|
[54] |
|
[55] |
|
[56] |
|
[57] |
|
[58] |
|
[59] |
|
[60] |
|
[61] |
|
[62] |
|
[63] |
|
/
〈 |
|
〉 |