Research Progress in Treatment Principles of Acute Closed Soft Tissue Injuries

Bingying ZHANG; Xiaohan ZHANG; Yi QIAN; Wenbo TANG; Feng GAO; Jingbin ZHOU

doi:10.3881/j.issn.1000-503X.16073

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Acta Academiae Medicinae Sinicae ›› 2024, Vol. 46 ›› Issue (6) : 828-835. DOI: 10.3881/j.issn.1000-503X.16073

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Research Progress in Treatment Principles of Acute Closed Soft Tissue Injuries

Bingying ZHANG ¹ ,
Xiaohan ZHANG ¹ ,
Yi QIAN ²^,³ ,
Wenbo TANG ¹ ,
Feng GAO ²^,³ ,
Jingbin ZHOU ³^,⁴

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Abstract

This article comprehensively reviews the research progress in the management principles of acute closed soft tissue injuries,summarizing the retention and updates of the four main principles (RICE,PRICE,POLICE,and PEACE&LOVE) at different stages.Traditional methods such as compression,elevation,rest,and protection remain valuable.However,with the advancement in rehabilitation philosophy,early active rehabilitation plays an increasingly important role in the tissue healing process.Traditional cold therapy remains a choice because of its benefits.Non-steroidal anti-inflammatory drugs play a positive role in relieving the acute pain and swelling and improving the function of soft tissue,being preferred by both patients and medical practitioners.Therefore,advantages outweigh disadvantages in the clinical application of non-steroidal anti-inflammatory drugs.Finally,modern medical models have begun to incorporate more social and psychological factors,focusing on patients’ mental state and social environment,while guiding patients to actively participate in the rehabilitation process,which can accelerate the recovery process and improve treatment outcomes.

Key words

acute soft tissue injury / sports injury / treatment principles / sports rehabilitation

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Bingying ZHANG , Xiaohan ZHANG , Yi QIAN , et al . Research Progress in Treatment Principles of Acute Closed Soft Tissue Injuries[J]. Acta Academiae Medicinae Sinicae. 2024, 46(6): 828-835 https://doi.org/10.3881/j.issn.1000-503X.16073

References

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[1]	国家创伤医学中心, 中华医学会疼痛学分会, 中国医师协会创伤外科医师分会, 等. 急性闭合性软组织损伤诊疗与疼痛管理专家共识[J]. 中华医学杂志, 2021, 101(21):1553-1559.DOI:10.3760/cma.j.cn112137-20210123-00225. Cited in this article [1]

[2]	Mirkin G, Hoffman M. The sportsmedicine book[M]. New York: Little Brown, 1978:94-94. Cited in this article [2]

[3]

Bleakley

, Davison

. Management of acute soft tissue injury using protection rest ice compression and elevation:recommendations from the Association of Chartered Physiotherapists in Sports and Exercise Medicine (ACPSM)[EB/OL]. [2024-03-13]. http://uir.ulster.ac.uk/17913/1/ACPSM_Physio_Book.pdf

http://uir.ulster.ac.uk/17913/1/ACPSM_Physio_Book.pdf

Cited in this article [1]

[4]	Bleakley CM, Glasgow P, MacAuley DC. PRICE needs updating,should we call the POLICE[J]. Br J Sports Med, 2012, 46(4):220-221.DOI:10.1136/bjsports-2011-090297. Cited in this article [2]

[5]	Dubois B, Esculier JF. Soft-tissue injuries simply need PEACE and LOVE[J]. Br J Sports Med, 2020, 54(2):72-73.DOI:10.1136/bjsports-2019-101253. Cited in this article [2]

[6]	Hansrani V, Khanbhai M, Bhandari S, et al. The role of compression in the management of soft tissue ankle injuries:a systematic review[J]. Eur J Orthop Surg Traumatol, 2015, 25(6):987-995.DOI:10.1007/s00590-015-1607-4. Cited in this article [1]

[7]	Sultan MJ, McKeown A, McLaughlin I, et al. Elastic stockings or tubigrip for ankle sprain:a randomised clinical trial[J]. Injury, 2012, 43(7):1079-1083.DOI:10.1016/j.injury.2012.01.026. Cited in this article [1]

[8]	Borra V, Berry DC, Zideman D, et al. Compression wrapping for acute closed extremity joint injuries:a systematic review[J]. J Athl Train, 2020, 55(8):789-800.DOI:10.4085/1062-6050-0093.20. Cited in this article [2]

[9]	Vuurberg G, Hoorntje A, Wink LM, et al. Diagnosis,treatment and prevention of ankle sprains:update of an evidence-based clinical guideline[J]. Br J Sports Med, 2018, 52(15):956.DOI:10.1136/bjsports-2017-098106. Cited in this article [1]

[10]	Rucinkski TJ, Hooker DN, Prentice WE, et al. The effects of intermittent compression on edema in postacute ankle sprains[J]. J Orthop Sports Phys Ther, 1991, 14(2):65-69.DOI:10.2519/jospt.1991.14.2.65. Cited in this article [1]

[11]	Seo DK, Kang HW, Ahn DS, et al. Effect of leg elevation height on reduced swelling of patients of postoperative acute ankle fractures[J]. J Korean Foot Ankle Soc, 2020, 24(1):31-36.DOI:10.14193/jkfas.2020.24.1.31. Cited in this article [2]

[12]	Rabe E, Partsch H, Morrison N, et al. Risks and contraindications of medical compression treatment-a critical reappraisal.An international consensus statement[J]. Phlebology, 2020, 35(7):447-460.DOI:10.1177/0268355520909066. Cited in this article [1]

[13]	Bring DK, Reno C, Renstorm P, et al. Joint immobilization reduces the expression of sensory neuropeptide receptors and impairs healing after tendon rupture in a rat model[J]. J Orthop Res, 2009, 27(2):274-280.DOI:10.1002/jor.20657. Cited in this article [1]

[14]	Eliasson P, Andersson T, Aspenberg P. Rat achilles tendon healing:mechanical loading and gene expression[J]. J Appl Physiol (1985), 2009, 107(2):399-407.DOI:10.1152/japplphysiol.91563.2008. Cited in this article [1]

[15]	Bleakley CM, O’Connor SR, Tully MA, et al. Effect of accelerated rehabilitation on function after ankle sprain:randomised controlled trial[J]. BMJ, 2010, 340:c1964.DOI:10.1136/bmj.c1964. Cited in this article [1]

[16]	Wang Z, Qi F, Luo H, et al. Inflammatory microenvironment of skin wounds[J]. Front Immunol, 2022, 13:789274.DOI:10.3389/fimmu.2022.789274. Cited in this article [1]

[17]	Singh DP, Barani Lonbani Z, Woodruff MA, et al. Effects of topical icing on inflammation,angiogenesis,revascularization,and myofiber regeneration in skeletal muscle following contusion injury[J]. Front Physiol, 2017, 8:93.DOI:10.3389/fphys.2017.00093. Cited in this article [2]

[18]	Høier B, Olsen K, Nyberg M, et al. Contraction-induced secretion of VEGF from skeletal muscle cells is mediated by adenosine[J]. Am J Physiol Heart Circ Physiol, 2010, 299(3):857-862.DOI:10.1152/ajpheart.00082.2010. Cited in this article [1]

[19]	Gustafsson T, Puntschart A, Kaijser L, et al. Exercise-induced expression of angiogenesis-related transcription and growth factors in human skeletal muscle[J]. Am J Physiol, 1999, 276(2):679-685.DOI:10.1152/ajpheart.1999.276.2.H679. Cited in this article [1]

[20]	Hittel DS, Axelson M, Sarna N, et al. Myostatin decreases with aerobic exercise and associates with insulin resistance[J]. Med Sci Sports Exerc, 2010, 42(11):2023-2029.DOI:10.1249/MSS.0b013e3181e0b9a8. Cited in this article [1]

[21]	Sandri M, Lin J, Handschin C, et al. PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription[J]. Proc Natl Acad Sci U S A, 2006, 103(44):16260-16265.DOI:10.1073/pnas.0607795103. Cited in this article [1]

[22]	Du R, Sun W, He F, et al. Early weight-bearing rehabilitation protocol after anterior cruciate ligament reconstruction[J]. J Vis Exp, 2024, 205:e65993.DOI:10.3791/65993. Cited in this article [1]

[23]	Glasgow P, Phillips N, Bleakley C. Optimal loading:key variables and mechanisms[J]. Br J Sports Med, 2015, 49(5):278-279.DOI:10.1136/bjsports-2014-094443. Cited in this article [2]

[24]	Arampatzis A, Karamanidis K, Albracht K. Adaptational responses of the human achilles tendon by modulation of the applied cyclic strain magnitude[J]. J Exp Biol, 2007, 210(15):2743-2753.DOI:10.1242/jeb.003814. Cited in this article [1]

[25]	Zhao R, Zhao M, Zhang L. Efficiency of jumping exercise in improving bone mineral density among premenopausal women:a meta-analysis[J]. Sports Med, 2014, 44(10):1393-1402.DOI:10.1007/s40279-014-0220-8. Cited in this article [1]

[26]	Wolpert DM, Diedrichsen J, Flanagan JR. Principles of sensorimotor learning[J]. Nat Rev Neurosci, 2011, 12(12):739-751.DOI:10.1038/nrn3112. Cited in this article [1]

[27]	陈柯羽, 刘纾羽, 吉祥, 等. 中国康复医学领域中的人工智能及发展趋势分析[J]. 中国医学科学院学报, 2021, 43(5):773-784.DOI:10.3881/j.issn.1000-503X.13926. Cited in this article [1]

[28]	Mirkin G. Why ice delays recovery[EB/OL]. [2015-09-16]. https://drmirkin.com/fitness/why-ice-delays-recovery.htm https://drmirkin.com/fitness/why-ice-delays-recovery.htm Cited in this article [1]

[29]	Khoshnevis S, Craik NK, Diller KR. Cold-induced vasoconstriction may persist long after cooling ends:an evaluation of multiple cryotherapy units[J]. Knee Surg Sports Traumatol Arthrosc, 2015, 23(9):2475-2483.DOI:10.1007/s00167-014-2911-y. Cited in this article [1]

[30]	Bleakley CM, Costello JT, Glasgow PD. Should athletes return to sport after applying ice? A systematic review of the effect of local cooling on functional performance[J]. Sports Med, 2012, 42(1):69-87.DOI:10.2165/11595970-000000000-00000. Cited in this article [1]

[31]	Zare P, Ghoraishian M, Faghih Khorasani A. A three-dimensional model of transient bioheat transfer in the lower extremity during cryotherapy[J]. Proc Inst Mech Eng H, 2021, 235(12):1413-1420.DOI:10.1177/09544119211035855. Cited in this article [2]

[32]	Fousekis K, Tsepis E. Minor soft tissue injuries may need PEACE in the acute phase,but moderate and severe injuries require CARE[J]. J Sports Sci Med, 2021, 20(4):799-800.DOI:10.52082/jssm.2021.799. Cited in this article [2]

[33]	Vieira Ramos G, Pinheiro CM, Messa SP, et al. Cryotherapy reduces inflammatory response without altering muscle regeneration process and extracellular matrix remodeling of rat muscle[J]. Sci Rep, 2016, 6(1):18525.DOI:10.1038/srep18525. Cited in this article [1]

[34]	Sapega AA, Heppenstall RB, Sokolow DP, et al. The bioenergetics of preservation of limbs before replantation.The rationale for intermediate hypothermia[J]. J Bone Joint Surg Am, 1988, 70(10):1500-1513. Cited in this article [1]

[35]	Bleakley CM, Glasgow P, Webb MJ. Cooling an acute muscle injury:can basic scientific theory translate into the clinical setting[J]. Br J Sports Med, 2012, 46(4):296-298.DOI:10.1136/bjsm.2011.086116. Cited in this article [2]

[36]	Ihsan M, Watson G, Lipski M, et al. Influence of postexercise cooling on muscle oxygenation and blood volume changes[J]. Med Sci Sports Exerc, 2013, 45(5):876-882.DOI:10.1249/MSS.0b013e31827e13a2. Cited in this article [1]

[37]	Pournot H, Bieuzen F, Louis J, et al. Time-course of changes in inflammatory response after whole-body cryotherapy multi exposures following severe exercise[J]. PLoS One, 2011, 6(7):e22748.DOI:10.1371/journal.pone.0022748. Cited in this article [1]

[38]	Ziemann E, Olek RA, Kujach S, et al. Five-day whole-body cryostimulation,blood inflammatory markers,and performance in high-ranking professional tennis players[J]. J Athl Train, 2012, 47(6):664-672.DOI:10.4085/1062-6050-47.6.13. Cited in this article [1]

[39]	Guilhem G, Hug F, Couturier A, et al. Effects of air-pulsed cryotherapy on neuromuscular recovery subsequent to exercise-induced muscle damage[J]. Am J Sports Med, 2013, 41(8):1942-1951.DOI:10.1177/0363546513490648. Cited in this article [1]

[40]	Ingram J, Dawson B, Goodman C, et al. Effect of water immersion methods on post-exercise recovery from simulated team sport exercise[J]. J Sci Med Sport, 2009, 12(3):417-421.DOI:10.1016/j.jsams.2007.12.011. Cited in this article [1]

[41]	Pointon M, Duffield R, Cannon J, et al. Cold water immersion recovery following intermittent-sprint exercise in the heat[J]. Eur J Appl Physiol, 2012, 112(7):2483-2494.DOI:10.1007/s00421-011-2218-3. Cited in this article [1]

[42]	Leeder J, Gissane C, van Someren K, et al. Cold water immersion and recovery from strenuous exercise:a meta-analysis[J]. Br J Sports Med, 2012, 46(4):233-240.DOI:10.1136/bjsports-2011-090061. Cited in this article [1]

[43]	Pointon M, Duffield R. Cold water immersion recovery after simulated collision sport exercise[J]. Med Sci Sports Exerc, 2012, 44(2):206-216.DOI:10.1249/MSS.0b013e31822b0977. Cited in this article [1]

[44]	Fragala MS, Jajtner AR, Townsend JR, et al. Leukocyte IGF-1 receptor expression during muscle recovery[J]. Med Sci Sports Exerc, 2015, 47(1):92-99.DOI:10.1249/MSS.0000000000000392. Cited in this article [1]

[45]	Peake JM, Roberts LA, Figueiredo VC, et al. The effects of cold water immersion and active recovery on inflammation and cell stress responses in human skeletal muscle after resistance exercise[J]. J Physiol, 2017, 595(3):695-711.DOI:10.1113/JP272881. Cited in this article [1]

[46]	Gonzalez AM, Stout JR, Jajtner AR, et al. Effects of β-hydroxy-β-methylbutyrate free acid and cold water immersion on post-exercise markers of muscle damage[J]. Amino Acids, 2014, 46(6):1501-1511.DOI:10.1007/s00726-014-1722-2. Cited in this article [1]

[47]	Roberts LA, Nosaka K, Coombes JS, et al. Cold water immersion enhances recovery of submaximal muscle function after resistance exercise[J]. Am J Physiol Regul Integr Comp Physiol, 2014, 307(8):998-1008.DOI:10.1152/ajpregu.00180.2014. Cited in this article [1]

[48]	Jajtner AR, Hoffman JR, Gonzalez AM, et al. Comparison of the effects of electrical stimulation and cold-water immersion on muscle soreness after resistance exercise[J]. J Sport Rehabil, 2015, 24(2):99-108.DOI:10.1123/jsr.2013-0113. Cited in this article [1]

[49]	Tseng CY, Lee JP, Tsai YS, et al. Topical cooling (icing) delays recovery from eccentric exercise-induced muscle damage[J]. J Strength Cond Res, 2013, 27(5):1354-1361.DOI:10.1519/JSC.0b013e318267a22c. Cited in this article [1]

[50]	Scott A, Khan KM, Roberts CR, et al. What do we mean by the term “inflammation”? A contemporary basic science update for sports medicine[J]. Br J Sports Med, 2004, 38(3):372-380.DOI:10.1136/bjsm.2004.011312. Cited in this article [1]

[51]	Rice D, McNair PJ, Dalbeth N. Effects of cryotherapy on arthrogenic muscle inhibition using an experimental model of knee swelling[J]. Arthritis Rheum, 2009, 61(1):78-83.DOI:10.1002/art.24168. Cited in this article [1]

[52]	Wang ZR, Ni GX. Is it time to put traditional cold therapy in rehabilitation of soft-tissue injuries out to pasture[J]. World J Clin Cases, 2021, 9(17):4116-4122.DOI:10.12998/wjcc.v9.i17.4116. Cited in this article [1]

[53]	Rouzer CA, Marnett LJ. Structural and chemical biology of the interaction of cyclooxygenase with substrates and non-steroidal anti-inflammatory drugs[J]. Chem Rev, 2020, 120(15):7592-7641.DOI:10.1021/acs.chemrev.0c00215. Cited in this article [1]

[54]	Ziltener JL, Leal S, Fournier PE. Non-steroidal anti-inflammatory drugs for athletes:an update[J]. Ann Phys Rehabil Med, 2010, 53(4):278-288.DOI:10.1016/j.rehab.2010.03.001. Cited in this article [1]

[55]	Paoloni JA, Milne C, Orchard J, er al. Non-steroidal anti-inflammatory drugs in sports medicine:guidelines for practical but sensible use[J]. Br J Sports Med, 2009, 43(11):863-865.DOI:10.1136/bjsm.2009.059980. Cited in this article [1]

[56]	De Sire A, Marotta N, Lippi L, et al. Pharmacological treatment for acute traumatic musculoskeletal pain in athletes[J]. Medicina (Kaunas), 2021, 57(11):1208.DOI:10.3390/medicina57111208. Cited in this article [1]

[57]	Henrot P, Blervaque L, Dupin I, et al. Cellular interplay in skeletal muscle regeneration and wasting:insights from animal models[J]. J Cachexia Sarcopenia Muscle, 2023, 14(2):745-757.DOI:10.1002/jcsm.13103. Cited in this article [1]

[58]	Dufresne SS, Frenette J, Dumont NA. Inflammation et régénér-ation musculaire-Une arme à double tranchant [Inflammation and muscle regeneration,a double-edged sword][J]. Med Sci (Paris), 2016, 32(6-7):591-597.DOI:10.1051/medsci/20163206022. Cited in this article [1]

[59]	Dumont N, Lepage K, Côté CH, et al. Mast cells can modulate leukocyte accumulation and skeletal muscle function following hindlimb unloading[J]. J Appl Physiol, 2007, 103(1):97-104.DOI:10.1152/japplphysiol.01132.2006. Cited in this article [1]

[60]	Duchesne E, Bouchard P, Roussel MP, et al. Mast cells can regulate skeletal muscle cell proliferation by multiple mechanisms[J]. Muscle Nerve, 2013, 48(3):403-414.DOI:10.1002/mus.23758. Cited in this article [1]

[61]	Bondesen BA, Mills ST, Pavlath GK. The COX-2 pathway regulates growth of atrophied muscle via multiple mechanisms[J]. Am J Physiol Cell Physiol, 2006, 290(6):1651-1659.DOI:10.1152/ajpcell.00518.2005. Cited in this article [1]

[62]	Bondesen BA, Mills ST, Kegley KM, et al. The COX-2 pathway is essential during early stages of skeletal muscle regeneration[J]. Am J Physiol Cell Physiol, 2004, 287(2):475-483.DOI:10.1152/ajpcell.00088.2004. Cited in this article [1]

[63]	Reynolds JF, Noakes TD, Schwellnus MP, et al. Non-steroidal anti-inflammatory drugs fail to enhance healing of acute hamstring injuries treated with physiotherapy[J]. S Afr Med J, 1995, 85(6):517-522. Cited in this article [1]

[64]	Mikkelsen UR, Langberg H, Helmark IC, et al. Local NSAID infusion inhibits satellite cell proliferation in human skeletal muscle after eccentric exercise[J]. J Appl Physiol, 2009, 107(5):1600-1611.DOI:10.1152/japplphysiol.00707.2009. Cited in this article [1]

[65]	Mackey AL, Kjaer M, Dandanell S, et al. The influence of anti-inflammatory medication on exercise-induced myogenic precursor cell responses in humans[J]. J Appl Physiol, 2007, 103(2):425-431.DOI:10.1152/japplphysiol.00157.2007. Cited in this article [1]

[66]	Cheung EV, Tidball JG. Administration of the non-steroidal anti-inflammatory drug ibuprofen increases macrophage concentrations but reduces necrosis during modified muscle use[J]. Inflamm Res, 2003, 52(4):170-176.DOI:10.1007/s000110300068. Cited in this article [1]

[67]	Thorsson O, Rantanen J, Hurme T, et al. Effects of nonsteroidal antiinflammatory medication on satellite cell proliferation during muscle regeneration[J]. Am J Sports Med, 1998, 26(2):172-176.DOI:10.1177/03635465980260020401. Cited in this article [1]

[68]	熊燕, 刘岩, 周敬滨, 等. 运动系统损伤外用NSAIDs治疗的临床实践指南(2024版)[J]. 中国循证医学杂志, 2024, 24(5):497-509.DOI:10.7507/1672-2531.202402074. Cited in this article [1]

[69]	Alshehri MG, Al-Asiri YA, Althobaiti AG, et al. The role of anti-inflammatory medications in physiotherapy with doctor for soft tissue injuries[J]. Jns, 2022, 32:1574-1585. Cited in this article [1]

[70]	Kim TH, Lee MS, Kim KH, et al. Acupuncture for treating acute ankle sprains in adults[J]. Cochrane Database Syst Rev, 2014, 2014(6):CD009065.DOI:10.1002/14651858.CD009065.pub2. Cited in this article [1]

[71]	Briet JP, Houwert RM, Hageman MGJS, et al. Factors associated with pain intensity and physical limitations after lateral ankle sprains[J]. Injury, 2016, 47(11):2565-2569.DOI:10.1016/j.injury.2016.09.016. Cited in this article [1]