
Research Progress in the Role of Testosterone in Male Depression
Jiamin FU, Qi GUO, Xiaoyu CHEN
Acta Academiae Medicinae Sinicae ›› 2025, Vol. 47 ›› Issue (2) : 274-280.
Abbreviation (ISO4): Acta Academiae Medicinae Sinicae
Editor in chief: Xuetao CAO
Research Progress in the Role of Testosterone in Male Depression
As the social pressure is increasing,the incidence of depression is growing.Testosterone is synthesized and secreted through the hypothalamic-pituitary-gonadal axis,which plays a regulatory role in men’s mental health.Studies have shown that low testosterone levels,clinical hypogonadism,and androgen deprivation therapy-induced testosterone deficiency are significantly associated with male depression,while there are still many uncertainties about the mechanism of their effects.Given that low testosterone levels may serve as a characteristic biomarker of male depression risk,testosterone replacement therapy may have a good therapeutic effect on male depression.This article focuses on assessing the role of testosterone levels and related clinical therapies in mood regulation in men.
testosterone / depression / testosterone replacement therapy / hypogonadism / androgen deprivation therapy
[1] |
|
[2] |
|
[3] |
|
[4] |
|
[5] |
|
[6] |
|
[7] |
|
[8] |
|
[9] |
|
[10] |
|
[11] |
|
[12] |
|
[13] |
|
[14] |
|
[15] |
|
[16] |
|
[17] |
|
[18] |
|
[19] |
|
[20] |
|
[21] |
|
[22] |
|
[23] |
|
[24] |
|
[25] |
|
[26] |
|
[27] |
|
[28] |
|
[29] |
尹一淑, 刘军莲, 王佳平, 等. 抑郁症相关发病机制研究进展[J]. 医学综述, 2022, 28(12):2368-2372.
|
[30] |
|
[31] |
|
[32] |
|
[33] |
|
[34] |
|
[35] |
|
[36] |
|
[37] |
|
[38] |
|
[39] |
|
[40] |
|
[41] |
|
[42] |
|
[43] |
|
[44] |
|
[45] |
|
[46] |
陈美惠, 贾佳, 曹燕丽, 等. 抑郁症患者性激素异常及治疗的研究进展[J]. 东南国防医药, 2021, 23(6):633-636.
|
[47] |
|
[48] |
|
[49] |
|
[50] |
|
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|
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