Research Progress of Autonomic Nerve Regulation in the Treatment of Myocardial Infarction

Shanshan LI; Mengting XIONG; Miaomiao GUO

doi:10.3881/j.issn.1000-503X.16150

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Acta Academiae Medicinae Sinicae ›› 2025, Vol. 47 ›› Issue (2) : 309-313. DOI: 10.3881/j.issn.1000-503X.16150

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Research Progress of Autonomic Nerve Regulation in the Treatment of Myocardial Infarction

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Abstract

The autonomic nervous system imbalance caused by the overactivation of the sympathetic nerve and the weakened activity of the parasympathetic nerve is closely related to the occurrence and development of myocardial infarction.Autonomic nerve regulation is a new therapeutic approach aiming at inhibiting sympathetic activity and increasing parasympathetic activity.It encompasses magnetic nerve stimulation,optogenetic neuromodulation,and microinjection of botulinum toxin,which could promote the rebalance of the autonomic nervous system,thereby curbing the deterioration of the cardiac function and reducing the occurrence of ventricular arrhythmias after myocardial infarction.This paper reviews the anatomical basis,mechanisms of action,and research advances in intervention strategies of the autonomic nervous system in myocardial infarction.

Key words

autonomic nerve / myocardial infarction / ventricular arrhythmia / vagus nerve

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Shanshan LI , Mengting XIONG , Miaomiao GUO. Research Progress of Autonomic Nerve Regulation in the Treatment of Myocardial Infarction[J]. Acta Academiae Medicinae Sinicae. 2025, 47(2): 309-313 https://doi.org/10.3881/j.issn.1000-503X.16150

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