Advances in Immunotherapy for Head and Neck Squamous Cell Carcinoma

Yue CAO, Chunmei BAI

Acta Academiae Medicinae Sinicae ›› 2025, Vol. 47 ›› Issue (5) : 850-862.

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Acta Academiae Medicinae Sinicae

Abbreviation (ISO4): Acta Academiae Medicinae Sinicae      Editor in chief: Xuetao CAO

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Acta Academiae Medicinae Sinicae ›› 2025, Vol. 47 ›› Issue (5) : 850-862. DOI: 10.3881/j.issn.1000-503X.16477
Review Articles

Advances in Immunotherapy for Head and Neck Squamous Cell Carcinoma

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Abstract

Head and neck squamous cell carcinoma(HNSCC) associated with a poor prognosis and diminished quality of life for patients is the most prevalent pathological type among head and neck tumors. Currently,the standard treatment modalities comprise systemic therapies(including chemotherapy,targeted therapy,and immunotherapy) and local therapies(surgery and radiotherapy).Immunotherapy,characterized by high specificity and low toxicity,is progressively expanding from advanced palliative care to the stage of locally advanced curative treatment and has demonstrated promising efficacy.This review summarizes the latest advances in immunotherapy for HNSCC,aiming to provide reference for optimizing clinical management strategies and facilitating the clinical research.

Key words

head and neck squamous cell carcinoma / immune checkpoint inhibitor / perioperative therapy / induction therapy

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Yue CAO , Chunmei BAI. Advances in Immunotherapy for Head and Neck Squamous Cell Carcinoma[J]. Acta Academiae Medicinae Sinicae. 2025, 47(5): 850-862 https://doi.org/10.3881/j.issn.1000-503X.16477

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