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Advances in Immunotherapy for Head and Neck Squamous Cell Carcinoma
Yue CAO, Chunmei BAI
Acta Academiae Medicinae Sinicae ›› 2025, Vol. 47 ›› Issue (5) : 850-862.
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Abbreviation (ISO4): Acta Academiae Medicinae Sinicae
Editor in chief: Xuetao CAO
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Advances in Immunotherapy for Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma(HNSCC) associated with a poor prognosis and diminished quality of life for patients is the most prevalent pathological type among head and neck tumors. Currently,the standard treatment modalities comprise systemic therapies(including chemotherapy,targeted therapy,and immunotherapy) and local therapies(surgery and radiotherapy).Immunotherapy,characterized by high specificity and low toxicity,is progressively expanding from advanced palliative care to the stage of locally advanced curative treatment and has demonstrated promising efficacy.This review summarizes the latest advances in immunotherapy for HNSCC,aiming to provide reference for optimizing clinical management strategies and facilitating the clinical research.
head and neck squamous cell carcinoma / immune checkpoint inhibitor / perioperative therapy / induction therapy
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