Advances in Clinical Application of Gastric Contrast-Enhanced Ultrasound for Gastric Cancer

Guanmo LIU, Hua LIANG, Yang GUI, Jie LI, Xin YE, Weiming KANG

Acta Academiae Medicinae Sinicae ›› 2025, Vol. 47 ›› Issue (5) : 716-724.

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Acta Academiae Medicinae Sinicae ›› 2025, Vol. 47 ›› Issue (5) : 716-724. DOI: 10.3881/j.issn.1000-503X.16604
Clinical Application of Gastrointestinal Ultrasound

Advances in Clinical Application of Gastric Contrast-Enhanced Ultrasound for Gastric Cancer

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Abstract

Gastric contrast-enhanced ultrasound includes oral contrast-enhanced ultrasound (OCUS) and double contrast-enhanced ultrasound (DCEUS),which can provide valuable clinical information about tumor morphology,vascular characteristics,and treatment responses.OCUS can clearly identify the gastric wall structure and the extent and depth of lesions by applying oral contrast agents.DCEUS,based on OCUS combined with venography,can display the anatomical and perfusion characteristics of lesions.In recent years,gastric contrast agents and imaging techniques have developed rapidly.However,the clinical application of gastric contrast-enhanced ultrasound is still in the developmental stage.This article reviews the clinical status of OCUS and DCEUS in the screening,diagnosis,staging,pathological typing,and treatment evaluation of gastric cancer.Studies have shown that gastric contrast-enhanced ultrasound has high sensitivity and specificity in the assessment of diagnosis and T-staging of gastric cancer.Furthermore,gastric contrast-enhanced ultrasound has the advantages of being cost-effective,convenient,non-invasive,free from radiation exposure,real-time,and easy to repeat.In the diagnosis and treatment of gastric cancer,it is expected to become one of the important imaging assessment tools.

Key words

oral contrast-enhanced ultrasound / double contrast-enhanced ultrasonound / gastric cancer / clinical application

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Guanmo LIU , Hua LIANG , Yang GUI , et al . Advances in Clinical Application of Gastric Contrast-Enhanced Ultrasound for Gastric Cancer[J]. Acta Academiae Medicinae Sinicae. 2025, 47(5): 716-724 https://doi.org/10.3881/j.issn.1000-503X.16604

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