Risk Factors for Secondary Uterine Arteriovenous Fistula After Induced Abortion

Chunying LI; Yang YE; Ping PENG; Yuhan LIU; Xinyan LIU

doi:10.3881/j.issn.1000-503X.17134

PDF(628 KB)

Acta Academiae Medicinae Sinicae ›› 2026, Vol. 48 ›› Issue (3) : 474-478. DOI: 10.3881/j.issn.1000-503X.17134

Original Articles

Risk Factors for Secondary Uterine Arteriovenous Fistula After Induced Abortion

Chunying LI ¹ ,
Yang YE ¹ ,
Ping PENG ¹ ,
Yuhan LIU ² ,
Xinyan LIU ¹

Author information +

History +

Abstract

Objective To explore the risk factors for secondary uterine arteriovenous fistula (UAVF) after induced abortion. Methods A retrospective case-control study was conducted.Fifty-two patients with secondary UAVF after induced abortion in Peking Union Medical College Hospital between January 2013 and January 2025 were enrolled in the patient group.According to a 1∶3 ratio,patients who underwent the same method of abortion to terminate pregnancy within the same two weeks but did not develop UAVF post-surgery were selected and included in the control group (n=156).The basic information was compared between the two groups. Multivariate logistic regression analysis was performed to identify the risk factors for UAVF after induced abortion. Results Multivariate logistic regression analysis showed that residual pregnancy tissue in the uterus was an independent risk factor for the occurrence of UAVF (OR=16.02,P=0.037).The patients with residual pregnancy tissue after induced abortion had a 16 fold higher incidence of secondary UAVF than the control group. Conclusions Residual pregnancy tissue in the uterus is an independent risk factor for secondary UAVF after induced abortion.Avoiding residual pregnancy tissue may reduce the occurrence of UAVF.

Key words

induced abortion / uterine arteriovenous fistula / risk factor

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

Chunying LI , Yang YE , Ping PENG , et al . Risk Factors for Secondary Uterine Arteriovenous Fistula After Induced Abortion[J]. Acta Academiae Medicinae Sinicae. 2026, 48(3): 474-478 https://doi.org/10.3881/j.issn.1000-503X.17134

References

List( Publishing order | Descend order by publishing year | Descend order by cited within ) Chart analysis

[1]	Cotter T, Arfa A, Moideen P, et al. Arteriovenous malformation of the uterus in a 41-year-old woman presenting as uterine bleeding[J]. Cureus, 2022, 14(3):e23646.DOI:10.7759/cureus.23646. Cited in this article [1]

[2]	Yazawa H, Soeda S, Hiraiwa T, et al. Prospective evaluation of the incidence of uterine vascular malformations developing after abortion or delivery[J]. J Minim Invasive Gynecol, 2013, 20(3):360-367.DOI:10.1016/j.jmig.2012.12.008. Cited in this article [1]

[3]

Lee

, Chan

, Chow

, et al. Endocrine glandderived vascular endothelial growth factor stimulates proliferation and tube formation in human uterine microvascular endothelial cell through the mitogenactivated protein kinase but not through the Akt pathway[J]. Fertil Steril, 2009, 91(5 Suppl):2163-2171.DOI:10.1016/j.fertnstert.2008.03.076.

Cited in this article [1]

[4]

Kazi

, Koos

. Estrogeninduced activation of hypoxiainducible factor 1alpha,vascular endothelial growth factor expression,and edema in the uterus are mediated by the phosphatidylinositol 3 kinase/Akt pathway[J]. Endocrinology, 2007, 148(5):2363-2374.DOI:10.1210/en.20061394.

Cited in this article [1]

[5]	Masood L, Rana AI, Khan ZA, et al. Imaging spectrum of acquired uterine vascular abnormalities with angiographic correlates,a pictorial review[J]. Egypt J Radiol Nucl Med, 2022, 53(1):6-7. Cited in this article [1]

[6]	Fleming H, Ostör AG, Pickel H, et al. Arteriovenous malformations of the uterus[J]. Obstet Gynecol, 1989, 73(2):209-214. Cited in this article [1]

[7]	Kwon JH, Kim GS. Obstetric iatrogenic arterial injuries of the uterus:diagnosis with US and treatment with transcatheter arterial embolization[J]. Radiographics, 2002, 22(1):35-46.DOI:10.1148/radiographics.22.1.g02ja0735. Cited in this article [1]

[8]	Taneja A, Chopra I, Kaur H, et al. Successful management of abnormal uterine bleeding from uterine arteriovenous malformations with progesterone in postabortal patients[J]. J Obstet Gynaecol Res, 2019, 45(6):1114-1117.DOI:10.1111/jog.13939. Cited in this article [1]

[9]	贾柠伊, 刘佳, 李坚. 子宫动静脉瘘诊断及治疗现状进展[J]. 中国妇产科临床杂志, 2019, 20(6):571-573. DOI:10.13390/j.issn.1672-1861.2019.06.031. Cited in this article [1]

[10]	Peitsidis P, Manolakos E, Tsekoura V, et al. Uterine arteriovenous malformations induced after diagnostic curettage:a systematic review[J]. Arch Gynecol Obstet, 2011, 284(5):1137-1151.DOI:10.1007/s00404-011-2067-7. Cited in this article [1]

[11]	Scribner D, Fraser R. Diagnosis of acquired uterine arteriovenous malformation by Doppler ultrasound[J]. J Emerg Med, 2016, 51(2):168-171.DOI:10.1016/j.jemermed.2016.04.028. Cited in this article [1]

[12]	Timmerman D, Wauters J, Van Calenbergh S, et al. Color Doppler imaging is a valuable tool for the diagnosis and management of uterine vascular malformations[J]. Ultrasound Obstet Gynecol, 2003, 21(6):570577.DOI:10.1002/uog.159. Cited in this article [1]

[13]	Timmerman D, Van den Bosch T, Peeraer K, et al. Vascular malformations in the uterus:ultrasonographic diagnosis and conservative management[J]. Eur J Obstet Gynecol Reprod Biol, 2000, 92(1):171178. DOI:10.1016/s03012115(0)004437. Cited in this article [1]

[14]	O’Brien P, Neyastani A, Buckley AR, et al. Uterine arteriovenous malformations:from diagnosis to treatment[J]. J Ultrasound Med, 2006, 25(11):1387-1392,1394-1395.DOI:10.7863/jum.2006.25.11.1387. Cited in this article [1]

[15]

Ghanaati

, Firouznia

, Moradi

, et al. Fertility outcomes after uterine artery embolization for symptomatic uterine arteriovenous malformations:a single-center retrospective study in 33 women[J]. Cardiovasc Intervent Radiol, 2022, 45(7):983-991.DOI:10.1007/s00270-022-03105-2.

Cited in this article [1]

[16]	中华医学会计划生育学分会, 中国优生优育协会生育健康与出生缺陷防控专委会,中国妇幼保健协会放射介入专业委员会. 早期妊娠相关子宫动静脉瘘诊治的中国专家共识(2022年版)[J]. 中国实用妇科与产科杂志, 2022, 38(3):284-289.DOI:10.19538/j.fk2022030109. Cited in this article [1]

[17]	Oukili H, Benlghazi A, Benmoussa M, et al. Arteriovenous malformation associated with trophoblastic retention postcesarean section:a case report and review[J]. Int J Surg Case Rep, 2024, 125:110620.DOI:10.1016/j.ijscr.2024.110620. Cited in this article [1]

[18]	Echarfaoui O, Lazhar H, Slaoui A, et al. Uterine arteriovenous malformations as a rare differential diagnosis of abnormal uterine bleeding:a case report[J]. Int J Surg Case Rep, 2025, 127:110900.DOI:10.1016/j.ijscr.2025.110900. Cited in this article [1]

[19]	Zhang W, Cui S, Mao Z, et al. Effect of direct surgical treatment in pregnancy-related uterine arteriovenous malformation[J]. BMC Pregnancy Childbirth, 2023, 23(1):673.DOI:10.1186/s12884023059613. Cited in this article [1]

[20]	Van Schoubroeck D, Van den Bosch T, Scharpe K, et al. Prospective evaluation of blood flow in the myometrium and uterine arteries in the puerperium[J]. Ultrasound Obstet Gynecol, 2004, 23(4):378381.DOI:10.1002/uog.963. Cited in this article [1]

[21]	谭伊琳, 迟晓艳, 张媛, 等. 妊娠相关子宫动静脉畸形手术治疗的回顾性分析[J]. 现代妇产科进展, 2022, 31(9):648652.DOI:10.13283/j.cnki.xdfckjz.2022.09.032. Cited in this article [1]