
Fabrication and Biomedical Application of Hyaluronic Acid Based Micro- and Nanogels
Xuedan Qian, Weijiang Yu, Junzhe Fu, Youxiang Wang, Jian Ji
Prog Chem ›› 2023, Vol. 35 ›› Issue (4) : 519-525.
Fabrication and Biomedical Application of Hyaluronic Acid Based Micro- and Nanogels
Hyaluronic acid is one of the primary components of the natural extracellular matrix, which has outstanding biocompatibility, biodegradability and excellent water retention capacity. Hyaluronic acid based micro- and nanogels have many desirable features of size adjustability, easy modification, deformability and structural integrity. They can not only meet most application requirements of bulk hydrogels, but also possess unique advantages due to small dimension, thus have been widely researched and used in biomedical field. This paper reviews the preparation methods and biomedical applications of hyaluronic acid based micro- and nanogels, and the future development of it is prospected.
hyaluronic acid / micro- and nanogels / crosslinking modification / biomedical application
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