New Dressings Based on Chitosan and Its Application

Quan Zhang, Siyu Duan, Zhongyuan Huo, Xinwang Meng, Jun Wang, Guohe Xu

Prog Chem ›› 2023, Vol. 35 ›› Issue (10) : 1450-1460.

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Prog Chem ›› 2023, Vol. 35 ›› Issue (10) : 1450-1460. DOI: 10.7536/PC230303
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New Dressings Based on Chitosan and Its Application

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Abstract

Chitosan has great potential in the fields of materials science and biomedicine because of its advantages such as coagulation, antibacterial, biocompatibility and biodegradation. This paper introduces the coagulation and bacteriostatic mechanism of chitosan, and lists the research progress of new dressings based on chitosan. According to the different morphology, the new dressings can be divided into the following types: fabric dressings based on chitosan, hydrogel dressings based on chitosan, spongy dressings based on chitosan, hydrocolloid dressings based on chitosan, asymmetric wettable dressings based on chitosan and frozen gel dressings based on chitosan. The experimental results of the new dressings based on chitosan in terms of antibacterial properties, in vitro coagulation properties, waterproof properties, breathable properties and mechanical properties were summarized. The application of new dressings based on chitosan in the treatment of diabetic foot ulcer, burn wound, inferior vena cava injury and endoscopic sinus surgery was summarized in detail. Finally, based on some problems existing in the new dressings based on chitosan (for example, the preparation process is greatly affected by the external environment conditions, some working mechanism of chitosan is still in the preliminary stage), the future development of the new dressings and their application are prospected.

Contents

1 Introduction

2 Working mechanism of new dressings based on chitosan

2.1 Hemostasis effect of chitosan

2.2 Bacteriostatic effect of chitosan

3 Research progress of new dressings based on chitosan

3.1 Fabric dressing based on chitosan

3.2 Hydrogel dressing based on chitosan

3.3 Spongy dressing based on chitosan

3.4 Hydrocolloidal dressing based on chitosan

3.5 Asymmetric wettability dressing based on chitosan

3.6 Frozen gel dressing based on chitosan

4 Application of new dressing based on chitosan

4.1 Diabetic foot ulcer

4.2 Burn wound

4.3 Inferior vena cava injury

4.4 Endoscopic sinus surgery

5 Conclusion and outlook

Key words

chitosan / new dressings / application

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Quan Zhang , Siyu Duan , Zhongyuan Huo , et al . New Dressings Based on Chitosan and Its Application[J]. Progress in Chemistry. 2023, 35(10): 1450-1460 https://doi.org/10.7536/PC230303

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Funding

Basic Scientific Research Funds for Universities Affiliated to Hebei Province(KY2022056)
Innovation and Entrepreneurship Training Program for Undergraduate Students of Hebei Agricultural University(2023114)
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