The use of grass control methods to explore ecological weed control techniques in tobacco fields is studied, with the aim of seeking new green prevention and control paths for weed control in tobacco fields. In this study, ryegrass, clover, lemongrass, peanut, horseshoe clover and other grass were selected for the experiment. Through the field plot experiment, the grass control effect of each treatment was investigated 20 and 60 days after the grass became turf, and the effects of each treatment on tobacco plant height, leaf number, leaf length and leaf width were investigated before tobacco topping. The results showed that ryegrass had the best control effect, with fast turf formation speed, over 90% control effect, and a long control time; the treatment of clover and thatch followed, while peanut and horseshoe clover were relatively poor, but they also had a certain inhibitory effect on the growth of weeds. The plant height, leaf length, and leaf width of tobacco treated with ryegrass, thatch grass, and clover grass were higher than those treated with tillage and natural grass, and there was a highly significant difference in leaf width. Ryegrass, clover, and thatch can be selected for ecological grass control in tobacco production.