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Acta Academiae Medicinae Sinicae
Acta Academiae Medicinae Sinicae
Abbreviation (ISO4):
Acta Academiae Medicinae Sinicae
Editor in chief:
Xuetao CAO
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Chinese Journal of Alzheimer's Disease and Related Disorders
Journal of Materials Engineering
Prog Geophy
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South Power Sys Technol
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Acta Academiae Medicinae Sinicae
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Fig.1
Reasons for poor solubility of peptide fragments
[
56
]
Fig.2
Methods for improving the solubility of peptides
[
57
⇓
⇓
⇓
⇓
⇓
~
63
]
Scheme 1
C terminal thioester solubilizing tag
[
67
]
Fig.3
Division of DGK hydrophilic peptides
[
67
]
Fig.4
Other C-terminal solubilizing tags
[
70
⇓
~
72
]
Fig.5
N-terminal solubilizing tags
[
73
,
74
]
Scheme 2
Base-liable N-terminal solubilizing tags
[
73
]
Fig.6
Side chain-based solubilizing tags
Scheme 3
Cys side chain solubilizing strategy developed by Brik et al
[
78
]
Scheme 4
Total chemical synthesis of histone H4
[
78
]
Scheme 5
Cys side chain solubilizing strategy developed by Yoshiya et al
[
81
]
Scheme 6
Total chemical synthesis of CP149
[
81
]
ALC
Scheme 7
Cys side chain solubilizing strategy developed by Deber et al
[
84
]
Scheme 8
Cys side chain solubilizing strategy developed by Li et al
[
85
]
Scheme 9
Total chemical synthesis of membrane protein FCER1G
[
85
]
Scheme 10
Lys side chain solubilizing strategy developed by Danishefsky et al
[
89
]
Scheme 11
Optimization of physical and chemical properties of hEPO peptide fragment
[
89
]
Scheme 12
Lys side chain solubilizing strategy developed by Hojo et al
[
91
]
Scheme 13
Total chemical synthesis of IL-2
[
91
]
Scheme 14
Lys side chain solubilizing strategy developed by Kay et al
[
94
]
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