The expression of wheat grain protein content in F1 as well as descendant F2 were studied.The result showed that the genes that control protein content transmitted to the descendants were mainly based on additive effect,but also with the non-additive effect.The grain protein content of F1 was highly related to the average value of both parents,and the protein content in descendant F2 appeared in normal distribution.The variance of general combining ability is larger than that of special combining ability.On parents,choicing of quality breeding,general combining ability is more important than the special combining ability,and should emphasize the appraisal and use of parents with high combining ability on protein content.The heritability in broad and narrow sense were calculated. Improved mothed on protein quantity is analysesed too.