In order to excavate a new plant-derived medicament for storage pests and effectively develop and utilize Stellera chamaejasme L., a poisonous weed, using different organs and extracts of Stellera chamaejasme L. as test materials, three common storage pests were tested by fumigation and avoidance methods. Among several conventional extracts of Stellera chamaejasme L., petroleum ether extract had the strongest activity. The lethal concentrations of petroleum ether extracts from flowers, leaves, roots, aerial parts and stems were 9.80 mg/L, 19.59 mg/L, 29.89 mg/L, 39.94 mg/L and 51.32 mg/L respectively; the lethal concentrations of petroleum ether extract from Stellera chamaejasme L. to Tribolium confusum (H.), Tribolium castaneum (Herbst) and Sitophilus oryzae (L.) were 9.80 mg/L, 14.47 mg/L and 18.66 mg/L, respectively. Tribolium confusum (H.) tends to be Stellera chamaejasme L and its extract, and Tribolium castaneum (Herbst) is repellent to it. The petroleum ether extract of Stellera chamaejasme can be used as a botanical drug for storage pests.