To evaluate the mechanized and coordinated application effect of special fertilizer for the tobacco root zone in the Fuxian Lake Basin, a field experiment was conducted with six treatments, including no fertilization, three formulations of local conventional compound fertilizer, root zone special fertilizer (9-9-32), and root zone special fertilizer (9-9-32) + citrate soluble potassium fertilizer. Three fertilization methods were tested: split broadcast application, conventional mechanical ridging fertilization, and integrated mechanical ridging combined with fertilization. The effects of integrated root zone fertilization on tobacco plant growth, development, and nutrient uptake were analyzed, followed by a comprehensive evaluation of the mechanized fertilization effect. The coefficient of variation for parameters such as single-hole fertilizer uniformity and fertilization spacing stability of the integrated machine was below 5%, meeting local requirements for mechanized fertilization. Compared with the local practice of split broadcast application of compound fertilizer + potassium sulfate (T2), the treatment with root zone special fertilizer + citrate soluble potassium fertilizer combined with mechanical root zone fertilization (T6) significantly promoted the growth, nutrient uptake, and accumulation of tobacco at different growth stages (P<0.05). The tobacco leaf yield and output value under T6 treatment were increased by 13.4% and 13.7%, respectively. Potassium, calcium, and magnesium contents in central leaves under T6 treatment increased by 15.3%, 15.8%, and 13.5%, respectively, while calcium and magnesium uptake increased by 79.9% and 97.6%. Principal component analysis of key parameters indicated that T6 had the best overall performance. In conclusion, combining root zone special fertilizer with integrated ridging and fertilization machinery significantly enhances tobacco yield and leaf potassium content, achieving both yield increase and quality improvement in tobacco.