In order to scientifically evaluate the suitable planting areas for white tea, this study first identifies the key climatic and topographic factors influencing white tea growth based on its biological characteristics. Leveraging meteorological observation data from 1991 to 2023 collected by basic meteorological stations in the study area and neighboring regions, elevation is incorporated as a covariate to perform high-resolution interpolation of zoning factors using the ANUSPLIN model. A comprehensive suitability assessment model for white tea, integrating climatic and topographic dimensions, is then constructed via the fuzzy mathematics-based comprehensive evaluation method. Taking Xianfeng County of Enshi Prefecture as an example, this research conducts a zoning analysis of white tea planting suitability. The results indicate that most areas in Xianfeng County exhibit favorable conditions in terms of heat, moisture, and sunlight. With the exception of high-altitude regions characterized by significant topographic relief, including the southern part of Huolongping Township, the southern part of Pingbaying Town, and the western and northeastern parts of Huangjindong Township, the majority of the county is suitable for white tea cultivation and possesses the natural endowment necessary for producing high-quality white tea. The fuzzy mathematics approach enables a holistic consideration of the impacts of natural factors such as climate and topography on white tea cultivation. The zoning outcomes provide a scientific basis for Xianfeng County to optimize the layout of white tea planting by integrating the current status of white tea production and regional natural resources.