In this study, we examined effects of phytoestrogen quercetin on the growth and skeletal development using amphibian Xenopus laevis as model animals. X. laevis were exposed to quercetin (50μg/L, 100μg/L, 200μg/L) from stage 46/47 to one month postmetamorphosis. The results showed that quercetin promoted body weigh gain and induced tail malformations. Exposure of 200μg/L quercetin caused vertebral malformations, which exhibited loss of a vertebra compared to the normal.
Cong Lin,, Qin Zhanfen, Jiang Xiangning, Zhou Jingming, Yang Lei,, Xu Xiaobai
. The Influence of Quercetin on the Growth and Skeletal development of Xenopus laevis[J]. Chinese Agricultural Science Bulletin, 2005
, 21(6)
: 164
-164
.
DOI: 10.11924/j.issn.1000-6850.0506164
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