Field experiment showed that fluoroglyeofen could effectively control the weeds such as Amarantus retroflexns L.,Acalypha australis L., Xanthium sibiricum part, Solanum nigrum in peanut field, but control effect is very low to controlling Chenopodium album L.and Abutilonheophrasti. The effect of mixture of fluoroglycefen and fenoxaprop-p-ethyl(6.9%ＥＷ) is higher than that of using only fluoroglycefen to controlling Digitaria sanguinalis L.and Echinohloa crnsgallic(L.) Beauv. Sprayed fluoroglycefen at the period of peanut 3～5 leaves,the suitable dosage is fluoroglycefen 375-475ml/hm2 or the mixture of fluoroglycefen and fenoxaprop-p-ethyl(6.9%ＥＷ)375+600～900 ml/hm2.These dosage are safe to peanut, and it control effect is higher and the cost is lower. fluoroglycefen is the substitute for lactofen.